Agonistic Antibodies

Agonistic antibodies mimic the action of natural ligands by binding to receptors and stimulating their signaling pathways. These reagents are valuable tools for investigating immune activation, costimulatory pathways, and therapeutic mechanisms in cancer, autoimmunity, and infectious disease.

Bio X Cell offers functional, in vivo-ready agonistic antibodies targeting key immune receptors such as CD40, OX40, 4-1BB (CD137), and GITR. By activating costimulatory signals, these antibodies can enhance T-cell responses, promote immune cell survival, and support studies of novel immunotherapy strategies.

All Bio X Cell agonistic antibodies are ultrapure (≥95% purity), feature low endotoxin levels (as low as ≤0.5 EU/mg), and are free from preservatives, stabilizers, and carrier proteins. Each lot is accompanied by a Certificate of Analysis (CoA) to ensure reproducibility and transparency in every experiment.