In Vivo Cell Specific Depletion

Bio X Cell provides functionally validated antibodies designed to selectively deplete specific immune cell populations in vivo. These reagents are widely used to complement or extend findings from genetic knockout mouse models and to determine the direct biological relevance of a given cell type in disease or immune function.

Depleting antibodies from Bio X Cell target key immune cell subsets, including CD4⁺ T cells, CD8⁺ T cells, B cells, NK cells, monocytes, macrophages, and dendritic cells. By enabling precise removal of defined populations, these antibodies are essential tools for dissecting immune mechanisms in infection, cancer, autoimmunity, and transplantation models.

All Bio X Cell depletion antibodies are ultrapure (≥95% purity), feature low endotoxin levels (as low as ≤0.5 EU/mg), and are free from preservatives, stabilizers, and carrier proteins. Each lot is accompanied by a Certificate of Analysis (CoA) to ensure reproducibility and transparency in every experiment.